An Intermediate State of Human BK Channel Reconstituted in Liposomes
نویسندگان
چکیده
منابع مشابه
BK Channel News
The large conductance Ca 2 -activated K channel (BK Ca ) is well positioned to assume diverse physiological functions because it is ubiquitously expressed in many cell types. Some of the functions recently proposed for this channel offer unexpected surprises, however, such as a role in innate immunity in neutrophil leukocytes (Ahluwalia et al., 2004), recognition as a heme-binding protein (Tang...
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BACKGROUND BK channels are usually activated by membrane depolarization and cytoplasmic Ca(2+). Especially,the activity of BK channel (α+β4) can be modulated by martentoxin, a 37 residues peptide, with Ca(2+)-dependent manner. gBK channel (glioma BK channel) and BK channel (α+β1) possessed higher Ca(2+) sensitivity than other known BK channel subtypes. METHODOLOGY AND PRINCIPAL FINDINGS The p...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2019
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2018.11.3097